Author: Lee, Kyung-Yil; Rhim, Jung-Woo; Kang, Jin-Han
Title: Kawasaki Disease: Laboratory Findings and an Immunopathogenesis on the Premise of a ""Protein Homeostasis System Document date: 2012_3_1
ID: 7ik3iszp_1
Snippet: Kawasaki disease (KD) is a self-limiting systemic inflammatory disease that occurs predominantly in children younger than 5 years of age. 1 Clinical manifestations of KD include prolonged fever (1-2 weeks, mean 10-11 days), conjunctival injection, oral lesions, polymorphous skin rashes, extremity changes, and cervical lymphadenopathy, all of which comprise diagnostic criteria. In addition, arthritis, eters; thus, laboratory findings are helpful f.....
Document: Kawasaki disease (KD) is a self-limiting systemic inflammatory disease that occurs predominantly in children younger than 5 years of age. 1 Clinical manifestations of KD include prolonged fever (1-2 weeks, mean 10-11 days), conjunctival injection, oral lesions, polymorphous skin rashes, extremity changes, and cervical lymphadenopathy, all of which comprise diagnostic criteria. In addition, arthritis, eters; thus, laboratory findings are helpful for diagnosing incomplete KD and evaluating patients for early prediction of IVIG non-responsiveness. Although some score systems for early detection of IVIG non-responders with a higher risk of CALs have been developed, 17, 18 further studies are needed for the early detection and proper treatment of initial IVIG non-responders.
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