Selected article for: "BAL fluid and mouse model"
Author: Xiao, Rui; Chen, Rongchang
Title: Neutrophil gelatinase-associated lipocalin as a potential novel biomarker for ventilator-associated lung injury
  • Document date: 2017_4_7
    • ID: 3e72pzui_18
    Snippet: To investigate the expression of NGAL in a mouse model of VALI, mice were subjected to low-or high-volume mechanical ventilation for 2 h or 4 h. As presented in Fig. 3A , NGAL mRNA expression levels in lung tissue demonstrated no difference between LV2 and LV4 exposure. However, a significant increase was present in HV4 compared with the HV2 group. Similarly, NGAL protein expression levels in lung tissue did not differ between the LV2 and LV4 gro.....
    Document: To investigate the expression of NGAL in a mouse model of VALI, mice were subjected to low-or high-volume mechanical ventilation for 2 h or 4 h. As presented in Fig. 3A , NGAL mRNA expression levels in lung tissue demonstrated no difference between LV2 and LV4 exposure. However, a significant increase was present in HV4 compared with the HV2 group. Similarly, NGAL protein expression levels in lung tissue did not differ between the LV2 and LV4 groups; however, they were markedly greater in the HV4 group compared with the HV2 group ( Fig. 3B and C) . Protein expression profiles of NGAL in BAL fluid and serum were similar to those in lung tissue ( Fig. 3B and C) .

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