Author: Joseph, Patrick; Godofsky, Eliot
Title: Outpatient Antibiotic Stewardship: A Growing Frontier—Combining Myxovirus Resistance Protein A With Other Biomarkers to Improve Antibiotic Use Document date: 2018_2_15
ID: 0emio4rl_2
Snippet: Clinical differentiation between a viral and bacterial URI can be challenging. Diagnostic uncertainty, combined with patient or family pressures, frequently facilitates the misuse of antibiotics [1] . Acute pharyngitis is primarily viral in adults, with only about 10% of patients having a bacterial cause, most commonly a group A beta-hemolytic streptococcus (GABHS) [2] . None of the symptoms, physical findings, or the clinical criteria scores are.....
Document: Clinical differentiation between a viral and bacterial URI can be challenging. Diagnostic uncertainty, combined with patient or family pressures, frequently facilitates the misuse of antibiotics [1] . Acute pharyngitis is primarily viral in adults, with only about 10% of patients having a bacterial cause, most commonly a group A beta-hemolytic streptococcus (GABHS) [2] . None of the symptoms, physical findings, or the clinical criteria scores are highly specific for differentiating GABHS from non-GABHS causes [3] . Despite the relatively high frequency of viral pharyngitis in adults, physicians prescribe antibiotics for 78% to 98% of patients with clinical pharyngitis in an effort not to miss bacterial GABHS pharyngitis [4, 5] . Furthermore, even though 90% of acute bronchitis is thought to be of viral etiology in the United States, the rate of antibiotic prescribing was shown to be between 60% and 80% [6] .
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