Title: Proceedings 31st Symposium ESVN-ECVN Document date: 2019_12_21
ID: 4526ne4l_80
Snippet: Glioblastoma (WHO grade IV, GBM) is a malignant, primary brain tumor which despite many years of research remains incurable. Tumor microenvironment plays an important role in growth, metastasis and response to treatment. Glioma cells overexpress and secrete protein †granulocyte macrophage colonyâ€stimulating factor (GMâ€CSF) that reprogram microglia accumulated in GBM into cells which potentiate tumor invasion and growth and suppress antitum.....
Document: Glioblastoma (WHO grade IV, GBM) is a malignant, primary brain tumor which despite many years of research remains incurable. Tumor microenvironment plays an important role in growth, metastasis and response to treatment. Glioma cells overexpress and secrete protein †granulocyte macrophage colonyâ€stimulating factor (GMâ€CSF) that reprogram microglia accumulated in GBM into cells which potentiate tumor invasion and growth and suppress antitumor immunity.
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