Selected article for: "cellular response and protein rna"
Author: Poltronieri, Palmiro; Sun, Binlian; Mallardo, Massimo
Title: RNA Viruses: RNA Roles in Pathogenesis, Coreplication and Viral Load
  • Document date: 2015_10_23
    • ID: 259cspey_65
    Snippet: In this review we highlighted the importance of cellular and viral RNAs in the cell response to RNA viruses, especially to retroviruses and endogenous L1 remnants of viral DNA integration. In addition, we reviewed several pathways involving small RNAs and short interfering RNAs deregulated in various states, from active infection to virusassociated cancers and defective immune signaling. A special role has been assigned to the deregulation of int.....
    Document: In this review we highlighted the importance of cellular and viral RNAs in the cell response to RNA viruses, especially to retroviruses and endogenous L1 remnants of viral DNA integration. In addition, we reviewed several pathways involving small RNAs and short interfering RNAs deregulated in various states, from active infection to virusassociated cancers and defective immune signaling. A special role has been assigned to the deregulation of interferon response and the inhibition of protein complexes in stress granules and P-bodies, RNA binding proteins, RISC components and the RNA silencing machinery.

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