Selected article for: "clean water and sanitation clean water"
Author: Carvalho, Miguel F.; Gill, Davinder
Title: Rotavirus vaccine efficacy: current status and areas for improvement
  • Document date: 2018_9_19
    • ID: 14a5861f_32
    Snippet: • Rotavirus gastroenteritis is the leading cause of diarrheal death, with an estimated annual toll of 200,000 children • Disease occurrence is modulated by access to clean water, sanitation, climate, poverty and nutrition, all of which contribute to environmental enteropathy • Current vaccines are widely deployed, regarded as safe but show inferior efficacy in low income nations where the incidence of disease is highest • More efficient v.....
    Document: • Rotavirus gastroenteritis is the leading cause of diarrheal death, with an estimated annual toll of 200,000 children • Disease occurrence is modulated by access to clean water, sanitation, climate, poverty and nutrition, all of which contribute to environmental enteropathy • Current vaccines are widely deployed, regarded as safe but show inferior efficacy in low income nations where the incidence of disease is highest • More efficient vaccines are required to address the needs of poorer countries • Research in areas such as mucosal immunity, adjuvants, systems vaccinology, delivery and stability will likely shape next generation Rotavirus vaccines

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