Author: Hajjar, L. A.; Mauad, T.; Galas, F. R. B. G.; Kumar, A.; da Silva, L. F. F.; Dolhnikoff, M.; Trielli, T.; Almeida, J. P.; Borsato, M. R. L.; Abdalla, E.; Pierrot, L.; Kalil Filho, R.; Auler, J. O. C.; Saldiva, P. H. N.; Hoff, P. M.
Title: Severe novel influenza A (H1N1) infection in cancer patients Document date: 2010_5_28
ID: 00rk8fb5_26
Snippet: Based on previous cases of H1N1 infection in noncancer patients, Ramsey et al. [6] described a significant proportion of patients with hypoxemic respiratory failure, specially when associated with comorbidities. Early intubation and admission in the ICU is prudent, given the rapid progression of hypoxemia. Based on current evidence, authors recommend patients should be managed with a low tidal volume open-lung strategy of ventilation, with PEEP t.....
Document: Based on previous cases of H1N1 infection in noncancer patients, Ramsey et al. [6] described a significant proportion of patients with hypoxemic respiratory failure, specially when associated with comorbidities. Early intubation and admission in the ICU is prudent, given the rapid progression of hypoxemia. Based on current evidence, authors recommend patients should be managed with a low tidal volume open-lung strategy of ventilation, with PEEP titrated based on FiO 2 to achieve adequate SpO 2 and low Pplat [21, 22] .
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