Author: Raeven, René H. M.; van Riet, Elly; Meiring, Hugo D.; Metz, Bernard; Kersten, Gideon F. A.
Title: Systems vaccinology and big data in the vaccine development chain Document date: 2018_11_13
ID: 3ywtkd3k_24
Snippet: To study the vaccine responses in the discovery phase, systems vaccinology methods can be used to study the mechanism of action of vaccines or adjuvants, both in vitro as well as in experimental animals (Fig. 2) . In vitro cell-based assays allow the gain of information on the magnitude and direction of the innate response, but they lack the possibility to study coherent interactions between innate and adaptive immune responses. Especially in the.....
Document: To study the vaccine responses in the discovery phase, systems vaccinology methods can be used to study the mechanism of action of vaccines or adjuvants, both in vitro as well as in experimental animals (Fig. 2) . In vitro cell-based assays allow the gain of information on the magnitude and direction of the innate response, but they lack the possibility to study coherent interactions between innate and adaptive immune responses. Especially in the transition from innate to adaptive responses, a lot of immunological information is still missing.
Search related documents:
Co phrase search for related documents- adaptive innate immune response and experimental animal: 1
- adaptive innate immune response and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- adaptive innate immune response and information gain: 1
- adaptive response and adjuvant vaccine: 1, 2, 3, 4, 5, 6, 7
- adaptive response and experimental animal: 1
- adaptive response and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- adaptive response and immunological information: 1
- adaptive response and information gain: 1
- adaptive response innate and adjuvant vaccine: 1, 2, 3, 4
- adaptive response innate and experimental animal: 1
- adaptive response innate and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- adaptive response innate and information gain: 1
- adaptive response innate transition and immune response: 1
- adjuvant vaccine and discovery phase: 1
- adjuvant vaccine and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cell base and immune response: 1, 2, 3
- direction magnitude and immune response: 1
- discovery phase and immune response: 1, 2
- experimental animal and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
Co phrase search for related documents, hyperlinks ordered by date