Author: Ahn, Jin Young; Sohn, Yujin; Lee, Su Hwan; Cho, Yunsuk; Hyun, Jong Hoon; Baek, Yae Jee; Jeong, Su Jin; Kim, Jung Ho; Ku, Nam Su; Yeom, Joon-Sup; Roh, Juhye; Ahn, Mi Young; Chin, Bum Sik; Kim, Young Sam; Lee, Hyukmin; Yong, Dongeun; Kim, Hyun Ok; Kim, Sinyoung; Choi, Jun Yong
Title: Use of Convalescent Plasma Therapy in Two COVID-19 Patients with Acute Respiratory Distress Syndrome in Korea Document date: 2020_4_6
ID: 1uwir5b8_19
Snippet: In Case 2, the patient showed lymphopenia from day 1, and it persisted even after clinical improvement with corticosteroid use. When the convalescent plasma was administered on day 6, lymphocyte count immediately rose to normal level (from 0.52 × 10 3 /µL to 1.21 × 10 3 /µL) and then remained in the normal range. Patients with severe COVID-19 pneumonia and ARDS also presented with lymphopenia in other studies. 11 Some authors hypothesized tha.....
Document: In Case 2, the patient showed lymphopenia from day 1, and it persisted even after clinical improvement with corticosteroid use. When the convalescent plasma was administered on day 6, lymphocyte count immediately rose to normal level (from 0.52 × 10 3 /µL to 1.21 × 10 3 /µL) and then remained in the normal range. Patients with severe COVID-19 pneumonia and ARDS also presented with lymphopenia in other studies. 11 Some authors hypothesized that continuous and gradual increases in lymphocyte count might be required for immunity against SARS-CoV-2 infection. 11 In SARS patients, lymphopenia existed at the onset of illness and persisted until the recovery period. 18, 19 These findings were consistent with the recovery of lymphocyte count with clinical improvement of Case 2 after the use of convalescent plasma.
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