Author: Pickett, Brett E.; Sadat, Eva L.; Zhang, Yun; Noronha, Jyothi M.; Squires, R. Burke; Hunt, Victoria; Liu, Mengya; Kumar, Sanjeev; Zaremba, Sam; Gu, Zhiping; Zhou, Liwei; Larson, Christopher N.; Dietrich, Jonathan; Klem, Edward B.; Scheuermann, Richard H.
Title: ViPR: an open bioinformatics database and analysis resource for virology research Document date: 2011_10_17
ID: 48ym7eti_11
Snippet: The ViPR annotation process extends the information contained in the representative RefSeq strain for each virus species. For example, multiple sequence alignment is used to map homologous regions across related virus genomes in order to transfer sequence region annotations, including mature peptide cleavage sites on polyproteins, to the genomes lacking annotations. Virus Orthologous Clusters (VOC) annotations group sets of proteins having simila.....
Document: The ViPR annotation process extends the information contained in the representative RefSeq strain for each virus species. For example, multiple sequence alignment is used to map homologous regions across related virus genomes in order to transfer sequence region annotations, including mature peptide cleavage sites on polyproteins, to the genomes lacking annotations. Virus Orthologous Clusters (VOC) annotations group sets of proteins having similar functions within large DNA virus families as determined using the OrthoMCL algorithm (16) .
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