Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_197
Snippet: These findings demonstrate that OSA exosomes contain proosteoblastic cargo which promotes healthy osteoblasts to increase bone deposition. Our study provides a preliminary understanding of the role of OSA-secreted exosomes and their impact on the bone microenvironment. Increased expression of programmed cell death ligand 1 (PD-L1) has been noted in a subset of human lymphomas and recently has been targeted with antibody therapy. The purpose of th.....
Document: These findings demonstrate that OSA exosomes contain proosteoblastic cargo which promotes healthy osteoblasts to increase bone deposition. Our study provides a preliminary understanding of the role of OSA-secreted exosomes and their impact on the bone microenvironment. Increased expression of programmed cell death ligand 1 (PD-L1) has been noted in a subset of human lymphomas and recently has been targeted with antibody therapy. The purpose of this study was to measure the expression of PD-L1 in canine diffuse large B-cell lymphoma (DLBCL) utilizing quantitative real time polymerase chain reaction (qPCR), and to determine if PD-L1 expression is correlated with progression free survival (PFS).
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