Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_202
Snippet: Materials & Methods: MCT1 and MCT4 expression in canine osteosarcoma were assessed with qRT-PCR, western blotting and IHC. Proliferation, apoptosis and oxygen consumption were evaluated using shRNA and small molecule inhibitors directed against MCT1 and MCT4. Metformin and doxorubicin were evaluated for their ability to synergize with MCT1/4 small molecule inhibitors......
Document: Materials & Methods: MCT1 and MCT4 expression in canine osteosarcoma were assessed with qRT-PCR, western blotting and IHC. Proliferation, apoptosis and oxygen consumption were evaluated using shRNA and small molecule inhibitors directed against MCT1 and MCT4. Metformin and doxorubicin were evaluated for their ability to synergize with MCT1/4 small molecule inhibitors.
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