Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_176
Snippet: To evaluate this hypothesis, we reviewed the medical records of 115 OSA patients with sufficient formalin-fixed tumor tissue available for immunohistochemical (IHC) analysis. Samples with at least 10% of malignant cells staining positive for HER2/neu were classified as HER2/neu+. Based on these criteria, 95/115 (82.6%) primary tumor samples were HER2/neu+. Additionally, 54 metastatic lesions from a total of 13 dogs were evaluated and 39/54 (72.2%.....
Document: To evaluate this hypothesis, we reviewed the medical records of 115 OSA patients with sufficient formalin-fixed tumor tissue available for immunohistochemical (IHC) analysis. Samples with at least 10% of malignant cells staining positive for HER2/neu were classified as HER2/neu+. Based on these criteria, 95/115 (82.6%) primary tumor samples were HER2/neu+. Additionally, 54 metastatic lesions from a total of 13 dogs were evaluated and 39/54 (72.2%) of these lesions were HER2/neu+. There was no correlation between HER2/neu expression by the primary tumor and HER2/neu expression by metastatic foci.
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