2017 ACVIM Forum Research Abstract Program

Therefore, the 1 mcg/kg IV dose of cosyntropin does not cause maximal adrenal response as does the standard 5 mcg/kg IV dose in dogs suspected of hypoadrenocorticism. The lower dose is not sufficient for ACTH stimulation testing in those patients suspected of hypoadrenocorticism. A veterinary-specific enzyme-linked immunoassay (ELISA) (SNAP Cortisol Test Kit, IDEXX, USA) is available to veterinarians for in-house diagnosis and management of canine hypo-and hyperadrenocorticism. However, analytical performance of the assay has not been reported in peer-reviewed literature. The purpose of this study was to investigate the precision of the ELISA, agreement of the ELISA with two chemiluminescence assays (CAs) at two reference laboratories, and the clinical implications of any identified bias.