2017 ACVIM Forum Research Abstract Program

There is clinical agreement between the ELISA and CA in most cases. Clinical disagreement would occur in 25.4% of cases. Equivocal results reported by the ELISA should be confirmed by a reference laboratory. While radioiodine is the treatment of choice for feline hyperthyroidism because of its safety and efficacy, dose determination of 131 I in cats remains controversial. The goal is to achieve a euthyroid state with one treatment, avoiding persistent hyperthyroidism or hypothyroidism. No method of dose determination has been able to consistently achieve this goal. We tested the hypothesis that a radioiodine dose determination based on thyroid scintigraphy would be associated with reduction in hypothyroidism without an increase in persistent hyperthyroidism at 6 months post radioiodine treatment compared with a fixed dose of 131 I.