Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_231
Snippet: Eight healthy purpose-bred dogs each received 2.4 nmol/kg of Levemir Ã’ and Toujeo Ã’ (0.1 U/kg and 0.4 U/kg, respectively, SC injection) on two different days, at least one week apart, in random order. Endogenous and exogenous insulin were measured hourly with the Mercodia Isoinsulin and the Mercodia canine insulin ELISA's. Blood glucose (BG) was measured every 5 minutes and glucose was administered intravenously at a variable rate with the goal.....
Document: Eight healthy purpose-bred dogs each received 2.4 nmol/kg of Levemir Ã’ and Toujeo Ã’ (0.1 U/kg and 0.4 U/kg, respectively, SC injection) on two different days, at least one week apart, in random order. Endogenous and exogenous insulin were measured hourly with the Mercodia Isoinsulin and the Mercodia canine insulin ELISA's. Blood glucose (BG) was measured every 5 minutes and glucose was administered intravenously at a variable rate with the goal of maintaining BG within 10% of baseline BG ("Isoglycemic clamp"). Glucose infusion rate and a decline in endogenous insulin were used to define exogenous insulin action.
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