Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_487
Snippet: State University, Fort Collins, CO, USA Liver disease associated with abnormal hepatocyte copper (Cu) concentrations occurs commonly in dogs. Excessive hepatic Cu results in hepatocyte damage from oxidative stress, resulting in cell death and subsequent necroinflammatory changes. Genetic mutations in Cu metabolism, impaired biliary excretion of Cu, and increased dietary Cu are thought to contribute to excessive hepatic Cu......
Document: State University, Fort Collins, CO, USA Liver disease associated with abnormal hepatocyte copper (Cu) concentrations occurs commonly in dogs. Excessive hepatic Cu results in hepatocyte damage from oxidative stress, resulting in cell death and subsequent necroinflammatory changes. Genetic mutations in Cu metabolism, impaired biliary excretion of Cu, and increased dietary Cu are thought to contribute to excessive hepatic Cu.
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