2017 ACVIM Forum Research Abstract Program

The reduction in LV systolic function post-sotalol is relatively mild in most dogs and percent change post-sotalol may not exceed previously reported within-day coefficients of variation for echocardiographic LV systolic function indices. Based on a 5-minute ECG, sotalol acutely improved ventricular ectopy. Chronic mitral valvular disease (CMVD) is the most common acquired canine heart disease, characterized by resultant volume overload firstly leading to left atrial enlargement. Occasionally, dogs with CMVD concomitant with renal insufficiency are found. Pathological interactions exist between cardiovascular diseases and renal disorders, which was recently defined as cardiovascular-renal disorders (CvRD) in veterinary medicine. Although the mechanisms of CvRD are not yet fully understood, cardiac diseases and renal dysfunction have recognized as both important determinant of prognosis to each other. Of tools for evaluation of cardiac function, speckle-tracking echocardiography (STE) is newer technique that allows more accurate assessment of left atrial (LA) as well as left ventricular (LV) functions. In the present study, the aims were to evaluate LA and LV function using STE, to assess the correlation between the class of cardiac and renal disease, and to investigate the correlation among the class of renal disease, echocardiographic variables, and laboratory variables in different stage of CMVD dogs and CMVD dogs concomitant with renal disorders.