Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_554
Snippet: Efm-induced inhibition of Tf growth was observed at concentrations as low as 10:1 Tf:Ef (P < 0.001) and was determined to be largely pH dependent (P < 0.01). Tf-induced cytopathogenicity, when co-cultured with Efm prior to infection of IPEC, was unaltered. However, pretreating IPEC monolayers with Efm reduced Tf adhesion (P = 0.002), suggesting a benefit of pre-treatment with Efm for cats at risk of Tf infection......
Document: Efm-induced inhibition of Tf growth was observed at concentrations as low as 10:1 Tf:Ef (P < 0.001) and was determined to be largely pH dependent (P < 0.01). Tf-induced cytopathogenicity, when co-cultured with Efm prior to infection of IPEC, was unaltered. However, pretreating IPEC monolayers with Efm reduced Tf adhesion (P = 0.002), suggesting a benefit of pre-treatment with Efm for cats at risk of Tf infection.
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