Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_616
Snippet: Alpha-enolase expression decreases in damaged tubules and increases in the glomeruli of older cats prior to the development of detectable CKD when compared to young, non-azotemic cats. Further studies will be required to determine whether these findings relate to the pathogenesis of CKD or could be used as an early diagnostic test for CKD. Metabolomics may be used for providing description of endogenous metabolites present in biological samples i.....
Document: Alpha-enolase expression decreases in damaged tubules and increases in the glomeruli of older cats prior to the development of detectable CKD when compared to young, non-azotemic cats. Further studies will be required to determine whether these findings relate to the pathogenesis of CKD or could be used as an early diagnostic test for CKD. Metabolomics may be used for providing description of endogenous metabolites present in biological samples in response to pathophysiological or external stimuli. The purpose of the present study was to use metabolomics to compare cats with feline idiopathic cystitis (FIC) or struvite plug (SP) with healthy cats.
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