Selected article for: "PD study and pk study"

Title: 2017 ACVIM Forum Research Abstract Program
  • Document date: 2017_6_15
  • ID: ri2w5iby_681
    Snippet: Esomeprazole is an S-enantiomer of omeprazole that has been reported to have more favourable pharmacokinetics and efficacious antacid properties in humans. However, the pharmacokinetics and effects on intragastric pH of esomeprazole in dogs have not been reported. To determine the pharmacokinetics of esomeprazole administered via various routes (PK study) and to investigate the effect of esomeprazole on intragastric pH using a Bravo pH monitoring.....
    Document: Esomeprazole is an S-enantiomer of omeprazole that has been reported to have more favourable pharmacokinetics and efficacious antacid properties in humans. However, the pharmacokinetics and effects on intragastric pH of esomeprazole in dogs have not been reported. To determine the pharmacokinetics of esomeprazole administered via various routes (PK study) and to investigate the effect of esomeprazole on intragastric pH using a Bravo pH monitoring system (PD study).

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