2017 ACVIM Forum Research Abstract Program

Dogs with a histopathologic diagnosis of inflammatory bowel disease (IBD) that had no other concurrent illness and had not received immunosuppressant therapy were eligible for inclusion in this study. Twenty dogs diagnosed with IBD and 20 healthy matched control dogs were included in the analysis. Variables compared between the two groups included MPV, PDW, and PCT, as well as mean platelet number (PLT), mean platelet component concentration (MPC), mean platelet component concentration distribution width (PCDW), mean platelet mass (MPM), and platelet dry mass distribution width (PMDW). Significant differences between dogs diagnosed with IBD and healthy controls were evaluated using a t-test (reported as the mean AE standard deviation) and a Receiver Operating Characteristic (ROC) curve. Additionally, the correlation between platelet indices and the CCECAI scores was evaluated using bivariate scatterplots and linear regression models to determine if any variables were predictive of disease severity.