Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_674
Snippet: There was a statistically significant difference in T max between liver disease cats and AMC cats (P = 0.03). T max was 4 hours in 7 liver cats versus 2 AMC cats and 1 hour in 3 liver cats versus 8 AMC cats. AUC and was not significantly different between the two groups; however, the calculated half-life of liver disease cats was significantly increased (*P < 0.004) compared to healthy AMC cats. There was a correlation between serum ALP (P = 0.00.....
Document: There was a statistically significant difference in T max between liver disease cats and AMC cats (P = 0.03). T max was 4 hours in 7 liver cats versus 2 AMC cats and 1 hour in 3 liver cats versus 8 AMC cats. AUC and was not significantly different between the two groups; however, the calculated half-life of liver disease cats was significantly increased (*P < 0.004) compared to healthy AMC cats. There was a correlation between serum ALP (P = 0.0003; r = 0.89), ALT (P = 0.003; r = 0.80) and total bilirubin (P = 0.001; r = 0.84) when compared to the serum half-life of mirtazapine.
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