Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_692
Snippet: During emergencies, it may be helpful for sildenafil to be administered rectally to respiratory distress patients. With the exception of an increased AUC, the pharmacokinetic characteristics of the rectally administered 10 mg/kg dose have been shown to be comparable to those of an orally administered 2 mg/kg dose. Mirtazapine 2% transdermal ointment (2% MZP) achieves clinically relevant serum concentrations in cats and results in increased body w.....
Document: During emergencies, it may be helpful for sildenafil to be administered rectally to respiratory distress patients. With the exception of an increased AUC, the pharmacokinetic characteristics of the rectally administered 10 mg/kg dose have been shown to be comparable to those of an orally administered 2 mg/kg dose. Mirtazapine 2% transdermal ointment (2% MZP) achieves clinically relevant serum concentrations in cats and results in increased body weights at a dose of 0.5 mg/kg. The purpose of this study was to evaluate the safety profile at an exaggerated dose.
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