Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_791
Snippet: Oral torsemide successfully reached therapeutic concentrations in blood, and resulted in mild pre-renal azotemia and electrolyte changes. These results suggest that oral torsemide may be employed as a clinically useful diuretic agent for management of congestive heart failure and fluid retention in the horse. Diuretic therapy has been limited to injectable formulations in the horse due to poor absorption of oral furosemide. The purpose of this st.....
Document: Oral torsemide successfully reached therapeutic concentrations in blood, and resulted in mild pre-renal azotemia and electrolyte changes. These results suggest that oral torsemide may be employed as a clinically useful diuretic agent for management of congestive heart failure and fluid retention in the horse. Diuretic therapy has been limited to injectable formulations in the horse due to poor absorption of oral furosemide. The purpose of this study was to determine whether oral torsemide produced clinically significant diuresis in healthy horses.
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