2017 ACVIM Forum Research Abstract Program

Of the 49 horses, 19 (39%) were PPID + and 8 (16%) were IR + . Of the 19 PPID + horses, only 2 (11%) were PPID + at the T0ACTH time point, whereas 19/19 (100%) were PPID + at T10ACTH. Six (32%) of 19 PPID + horses were hyperinsulinemic. Horses' ages ranged from 11 to 25 years of age (arithmetic mean 17 years) in the PPID + group. The most common clinical signs observed in the PPID + horses were delayed regional shedding, loss of epaxial muscle mass, regional adiposity, skeletal muscle atrophy and suspensory desmitis. PPID + was significantly (P = 0.023) associated with lameness (suspensory desmitis, tendon laxity, superficial digital flexor tendonitis). Of the horses that were lame, 70% were PPID + .