2017 ACVIM Forum Research Abstract Program

Treatment effects on wound temperature, vessel density, and wound size may indicate that ECFCs affect wound healing in equine distal limbs. Despite variability within the model, ECFC treated wounds had asignificantlypositiveeffectonwoundhealing. Septicemia remains a common clinical entity in neonatal foals with varying degrees of illness associated with the process, including cardiovascular shock. In some instances, clinical parameters such as heart rate, blood pressure and urine output may be unreliable or late indicators of inadequate tissue perfusion and poor global oxygenation status, thus providing limited guidance for timely therapy. Conversely, more invasive monitoring such as measurement of cardiac output (CO) and mixed venous oxygen saturation of hemoglobin have been advocated in some studies to better direct therapy (i.e. early goal-directed therapy) and improve outcome in people that are critically ill or in septic shock.