Title: 2017 ACVIM Forum Research Abstract Program Document date: 2017_6_15
ID: ri2w5iby_802
Snippet: Lithium chloride dosed at 0.15 mmol/kg bwt IV bolus was well tolerated by healthy adult horses and displayed pharmacokinetic parameters similar to that reported in other species. The SEA displayed acceptable internal validity but did not agree well with ICP-MS. The results of this study support further evaluation of LiCl for clinical use. Previous in-vitro studies using a voriconazole-poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)-b-poly(l.....
Document: Lithium chloride dosed at 0.15 mmol/kg bwt IV bolus was well tolerated by healthy adult horses and displayed pharmacokinetic parameters similar to that reported in other species. The SEA displayed acceptable internal validity but did not agree well with ICP-MS. The results of this study support further evaluation of LiCl for clinical use. Previous in-vitro studies using a voriconazole-poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)-b-poly(lactic-co-glycolic acid) thermogel (VORI-GEL) demonstrated sustained-release of voriconazole above therapeutic concentrations for most equine ocular fungal pathogens. The objective was to evaluate safety and voriconazole concentrations in ocular tissues and aqueous humor (AH) following subconjunctival injection of the VORI-GEL in horses.
Search related documents:
Co phrase search for related documents, hyperlinks ordered by date