Author: Caselli, Désirée; Aricò, Maurizio
Title: 2019-nCoV: Polite with children! Document date: 2020_2_11
ID: w7tbegc7_6
Snippet: Persistence of maternal protective immunity extending to the entire pediatric age appears very unlikely. No other posi-tively protective effect may be easily hypothesized. Are children cross-protected by having met other Coronaviruses? Coronaviruses (CoVs) is one of the common viruses that invade the lungs as rhinoviruses, respiratory syncytial virus (RSV), and influenza, which all have an RNA genome and are very frequent in children. Innate immu.....
Document: Persistence of maternal protective immunity extending to the entire pediatric age appears very unlikely. No other posi-tively protective effect may be easily hypothesized. Are children cross-protected by having met other Coronaviruses? Coronaviruses (CoVs) is one of the common viruses that invade the lungs as rhinoviruses, respiratory syncytial virus (RSV), and influenza, which all have an RNA genome and are very frequent in children. Innate immune evasion links to the innate immune responses elicited by respiratory and other (RNA) viruses. 6 One explanation could be that pneumonia results from virus-induced immune response causing destruction of pulmonary tissue. 7 Such mechanisms could be less effective in children.
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