Title: A Golgi retention signal in a membrane-spanning domain of coronavirus E1 protein Document date: 1991_10_1
ID: s4a8zs5a_4
Snippet: In addition to its role in protein processing, the Golgi complex is instrumental in correct sorting of protein traffic. Lysosomal hydrolases, regulated secretory proteins, and proteins destined for the apical or basolateral plasma membrane domains in polarized kidney epithelia are sorted in the trans-most cisternae of the Golgi, the trans-Golgi network (15, 43) . The cis-side of the Golgi complex may also be involved in sorting, since escaped ER .....
Document: In addition to its role in protein processing, the Golgi complex is instrumental in correct sorting of protein traffic. Lysosomal hydrolases, regulated secretory proteins, and proteins destined for the apical or basolateral plasma membrane domains in polarized kidney epithelia are sorted in the trans-most cisternae of the Golgi, the trans-Golgi network (15, 43) . The cis-side of the Golgi complex may also be involved in sorting, since escaped ER resident proteins must be separated from those that are transported forward (34) .
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