Author: Hawkins, John A.; Kaczmarek, Maria E.; Müller, Marcel A.; Drosten, Christian; Press, William H.; Sawyer, Sara L.
Title: A metaanalysis of bat phylogenetics and positive selection based on genomes and transcriptomes from 18 species Document date: 2019_6_4
ID: telmxmp4_18_1
Snippet: nment cleaning pipeline (with steps progressing from top to bottom in the graph). Unanimous second-consensus runs are defined as runs of more than three columns in a row where some minority of bat sequences agree with each other but disagree with those of all other bats. The final output contains only seven such runs with two or more species, and these are only up to three species and five amino acids long. (E) In each step of the alignment clean.....
Document: nment cleaning pipeline (with steps progressing from top to bottom in the graph). Unanimous second-consensus runs are defined as runs of more than three columns in a row where some minority of bat sequences agree with each other but disagree with those of all other bats. The final output contains only seven such runs with two or more species, and these are only up to three species and five amino acids long. (E) In each step of the alignment cleaning pipeline, weakly conserved sites are filtered at higher rates, enriching the final alignments for conserved sequences. "Strong," "Weak," and "None" conservation categories are as defined by Clustal (47) . Percent reduction in multiple sequence alignment column counts shown to the right. (F) Column conservation of the first 2,000 columns of the longest 2,000 alignments before and after exon filtering.
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