Author: Cha, Ran-hui; Yang, Seung Hee; Moon, Kyung Chul; Joh, Joon-Sung; Lee, Ji Yeon; Shin, Hyoung-Shik; Kim, Dong Ki; Kim, Yon Su
Title: A Case Report of a Middle East Respiratory Syndrome Survivor with Kidney Biopsy Results Document date: 2016_3_10
ID: rkwz1pwh_22
Snippet: The organ tropism of human coronavirus is primarily determined by the ability of the receptor binding protein to bind a cell surface receptor (5) . DPP 4 was identified as a functional receptor for MERS-CoV (5). DPP 4 is a widely expressed serine peptidase that exists on the surface of various cell types, and the renal expression levels of its messenger RNA and protein are high (6, 15) . DPP 4 is one of the major renal brush border membrane prote.....
Document: The organ tropism of human coronavirus is primarily determined by the ability of the receptor binding protein to bind a cell surface receptor (5) . DPP 4 was identified as a functional receptor for MERS-CoV (5). DPP 4 is a widely expressed serine peptidase that exists on the surface of various cell types, and the renal expression levels of its messenger RNA and protein are high (6, 15) . DPP 4 is one of the major renal brush border membrane proteins (7), and it is present in glomerular podocytes and capillaries, as well (8) . DPP 4 was previously co-stained with a MERS-CoV infected human kidney cell line (16) .
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