A 12-year follow-up study of combined treatment of post-severe acute respiratory syndrome patients with femoral head necrosis

Liu, Tiansheng; Ma, Jinchao; Su, Bin; Wang, Hao; Wang, Qi; Ma, Xinlong

All patients included in this study received the following treatment: 1) 70 mg weekly oral application of alendronate sodium for 12 consecutive years; 2) extracorporeal shock wave treatment was performed using HK.ESWL-Vm equipment (Huikang Med, Shenzhen, China). In brief, patients were fixed in a supine position with localization of the femoral necrosis region by scanning. Using 0.18-0.25 mJ/mm 2 energy density, 2-3 shocking sites were selected in single treatment for 1,000 times of shocking (60 per min). One treatment course thus consisted of 20,000-30,000 shocks. A total of 5-8 courses were performed within 2-3 months; 3) hyperbaric oxygen was performed at 1.5-fold of normal atmosphere pressure for 2 h. After 100 treatments (once daily), treatment was performed twice per week, with 5-7 days rest after every 30 treatments. In our department, each patient was re-examined monthly on VAS, Harris score and femoral joint MRI examination, which were used to calculate volume ratio of ONFH.