Title: A Golgi retention signal in a membrane-spanning domain of coronavirus E1 protein Document date: 1991_10_1
ID: s4a8zs5a_1
Snippet: S ORTING of newly synthesized proteins in the exocytic pathway is a fundamental problem in cell biology which has received a great deal of attention in recent years. Secreted and plasma membrane proteins follow a common pathway through the cell: from the ER, through the Golgi complex, to the cell surface (32) . Resident proteins ofthe ER and the Golgi complex are specifically retained . Although much is known regarding the signal sequence-mediate.....
Document: S ORTING of newly synthesized proteins in the exocytic pathway is a fundamental problem in cell biology which has received a great deal of attention in recent years. Secreted and plasma membrane proteins follow a common pathway through the cell: from the ER, through the Golgi complex, to the cell surface (32) . Resident proteins ofthe ER and the Golgi complex are specifically retained . Although much is known regarding the signal sequence-mediated translocation of proteins across the membrane of the ER (46) , less is known regarding the trafficking of proteins once they have entered this pathway.
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