Selected article for: "perinuclear area and TPIC internalization"
Author: Liu, Chunxi; Liu, Tingxian; Yu, Xiaoyue; Gu, Yizhu
Title: A preliminary study on the interaction between Asn-Gly-Arg (NGR)-modified multifunctional nanoparticles and vascular epithelial cells
  • Document date: 2017_4_1
    • ID: xio0g203_44
    Snippet: The results are shown in Fig. 5B . At 4 1C, red TPIC and green CAV1 overlapped into yellow stains, which demonstrated that TPIC could co-localize with CAV1. At 37 1C, the extent of colocalization increased and concentrated around the perinuclear area, suggesting that TPIC entered HUVEC together with CAV1 and that CAV1 participated in the internalization of TPIC. The colocalization behavior of TPIC and CAV1 was similar to that produced by the comb.....
    Document: The results are shown in Fig. 5B . At 4 1C, red TPIC and green CAV1 overlapped into yellow stains, which demonstrated that TPIC could co-localize with CAV1. At 37 1C, the extent of colocalization increased and concentrated around the perinuclear area, suggesting that TPIC entered HUVEC together with CAV1 and that CAV1 participated in the internalization of TPIC. The colocalization behavior of TPIC and CAV1 was similar to that produced by the combination of TPIC and CD13. The difference was TPIC could not cause clustering of CAV1.

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