Author: Whitehouse, Caroline; Burchell, Joy; Gschmeissner, Stephen; Brockhausen, Inka; Lloyd, Kenneth O.; Taylor-Papadimitriou, Joyce
Title: A Transfected Sialyltransferase That Is Elevated in Breast Cancer and Localizes to the medial/trans-Golgi Apparatus Inhibits the Development of core-2–based O-Glycans Document date: 1997_6_16
ID: pwgj97kz_51
Snippet: GlcNAc T is present and active. This in turn could affect the behavioral properties of the tumor cell. As a result of the complexity of the structure of the core-2-based oligosaccharides on MUC1 produced by MTSV1-7 (Lloyd et al., 1996) , a detailed structural analysis of the side chains is necessary to prove unequivocally that the decrease in GlcNAc content is due to a reduction in core-2 branching rather than a reduction in chain extension from .....
Document: GlcNAc T is present and active. This in turn could affect the behavioral properties of the tumor cell. As a result of the complexity of the structure of the core-2-based oligosaccharides on MUC1 produced by MTSV1-7 (Lloyd et al., 1996) , a detailed structural analysis of the side chains is necessary to prove unequivocally that the decrease in GlcNAc content is due to a reduction in core-2 branching rather than a reduction in chain extension from galactose in core-1.
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