Author: Whitehouse, Caroline; Burchell, Joy; Gschmeissner, Stephen; Brockhausen, Inka; Lloyd, Kenneth O.; Taylor-Papadimitriou, Joyce
Title: A Transfected Sialyltransferase That Is Elevated in Breast Cancer and Localizes to the medial/trans-Golgi Apparatus Inhibits the Development of core-2–based O-Glycans Document date: 1997_6_16
ID: pwgj97kz_47
Snippet: The number of each size of gold particles in the TGN was also estimated, and the distribution in the Golgi apparatus and TGN is shown in Table III . Quantitation of the 5-nm gold particles showed that the GalT was localized late in the Golgi stack, corresponding to the trans cisternae, and in the TGN (Table III and Fig. 10 ) as previously reported (Rabouille et al., 1995) . The larger (10-nm) gold particles identifying the â£2,3 SAT (O) show tha.....
Document: The number of each size of gold particles in the TGN was also estimated, and the distribution in the Golgi apparatus and TGN is shown in Table III . Quantitation of the 5-nm gold particles showed that the GalT was localized late in the Golgi stack, corresponding to the trans cisternae, and in the TGN (Table III and Fig. 10 ) as previously reported (Rabouille et al., 1995) . The larger (10-nm) gold particles identifying the â£2,3 SAT (O) show that this en-zyme is coexpressed in the trans cisternae but is equally well expressed earlier in the stack in an area probably corresponding to the medial cisternae. 26% of the â£2,3 sialyltransferase was also found in the TGN.
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