Author: Hsieh, Wen-Yeh; Kuan, Tang-Ching; Cheng, Kun-Shan; Liao, Yan-Chiou; Chen, Mu-Yuan; Lin, Pei-Heng; Hsu, Yuan-Chang; Huang, Chen-Yi; Hsu, Wei-Hua; Yu, Sheng-Yao; Lin, Chih-Sheng
Title: ACE/ACE2 Ratio and MMP-9 Activity as Potential Biomarkers in Tuberculous Pleural Effusions Document date: 2012_10_17
ID: zlzig0nn_32
Snippet: The ACE2 activity in tuberculous, pneumonia and adenocarcinoma effusions were 1.38 ± 0.58, 2.05 ± 1.40 and 2.38 ± 1.86 RFU/hour/ml (mean ± SD), respectively. Although a larger SD was determined in the pneumonia and adenocarcinoma groups, the ACE2 activity in both groups were significantly larger than that in the tuberculosis group (p < 0.05). In advanced assay, the data indicate that there were 75% tuberculosis (15/20) , 56% pneumonia (18/32).....
Document: The ACE2 activity in tuberculous, pneumonia and adenocarcinoma effusions were 1.38 ± 0.58, 2.05 ± 1.40 and 2.38 ± 1.86 RFU/hour/ml (mean ± SD), respectively. Although a larger SD was determined in the pneumonia and adenocarcinoma groups, the ACE2 activity in both groups were significantly larger than that in the tuberculosis group (p < 0.05). In advanced assay, the data indicate that there were 75% tuberculosis (15/20) , 56% pneumonia (18/32) and 50% adenocarcinoma (14/28) patients showed the ACE2 activity  1.80 RFU/hour/ml (75% of interquartile range in tuberculous effusions; IQR, 0.97-1.80). The data also support that the trend of decreased ACE2 activity in the pleural effusions with tuberculosis compared to those with pneumonia or adenocarcinoma. However, more patients should be further included in order to examine the proposition.
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