Author: Lee, Yun Jin
Title: Acute disseminated encephalomyelitis in children: differential diagnosis from multiple sclerosis on the basis of clinical course Document date: 2011_6_30
ID: zroskqmk_14
Snippet: The MRI abnormalities seen in ADEM are best defined using T2weighted images and fluid-attenuated inversion recovery (FLAIR) sequences (Fig. 2 ). Contrast enhancement is sometimes seen in acute lesions. Lesions associated with ADEM are typically bilateral but may be asymmetric and tend to be poorly marginated. Almost all patients have multiple lesions in the deep and subcortical white matter, while the periventricular white matter is generally spa.....
Document: The MRI abnormalities seen in ADEM are best defined using T2weighted images and fluid-attenuated inversion recovery (FLAIR) sequences (Fig. 2 ). Contrast enhancement is sometimes seen in acute lesions. Lesions associated with ADEM are typically bilateral but may be asymmetric and tend to be poorly marginated. Almost all patients have multiple lesions in the deep and subcortical white matter, while the periventricular white matter is generally spared. The thalami and basal ganglia are frequently affected (Fig. 2) , and lesions in these locations are often symmetrical 3, 22) . Brainstem and spinal cord abnormalities on MRI are common in ADEM 12) . The number of lesions varies, and their diameters range from <5 mm to 5 cm 1,3) . Values are presented as %.
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