Selected article for: "alternative reading frame and reading frame"

Author: Schlub, Timothy E; Buchmann, Jan P; Holmes, Edward C
Title: A Simple Method to Detect Candidate Overlapping Genes in Viruses Using Single Genome Sequences
  • Document date: 2018_8_7
  • ID: yiqdsf9z_37
    Snippet: where C is the empirical cumulative distribution function of the theoretical distribution of lengths calculated by permuting codons in the original coding sequence: that is, C(L) is the Simple Method to Detect Candidate Overlapping Genes . doi:10.1093/molbev/msy155 MBE probability of sampling an ORF length less than L on that specific reading frame. The value 1 À C(L) has an interpretation similar to that of a P value testing whether or not the .....
    Document: where C is the empirical cumulative distribution function of the theoretical distribution of lengths calculated by permuting codons in the original coding sequence: that is, C(L) is the Simple Method to Detect Candidate Overlapping Genes . doi:10.1093/molbev/msy155 MBE probability of sampling an ORF length less than L on that specific reading frame. The value 1 À C(L) has an interpretation similar to that of a P value testing whether or not the length L is sampled from the theoretical distribution of lengths calculated earlier. To correct this "P value" for the total number of alternative reading frame ORFs, s, in the original coding sequence the following equation is used:

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