Selected article for: "ace activity ratio and activity ratio"
Author: Hsieh, Wen-Yeh; Kuan, Tang-Ching; Cheng, Kun-Shan; Liao, Yan-Chiou; Chen, Mu-Yuan; Lin, Pei-Heng; Hsu, Yuan-Chang; Huang, Chen-Yi; Hsu, Wei-Hua; Yu, Sheng-Yao; Lin, Chih-Sheng
Title: ACE/ACE2 Ratio and MMP-9 Activity as Potential Biomarkers in Tuberculous Pleural Effusions
  • Document date: 2012_10_17
    • ID: zlzig0nn_23
    Snippet: Elevated ACE activity and an elevated ACE/ACE2 ratio were observed in exudative effusions. We then differentiated both ACE and ACE2 activities in the exudates according to different diseases, including tuberculosis, pneumonia, and adenocarcinoma. The ACE activity in the tuberculous pleural effusions was significantly higher than in pneumonia and adenocarcinoma effusions, by 2.89 (p < 0.001) and 2.62 (p < 0.001) fold, respectively ( Figure 4A ). .....
    Document: Elevated ACE activity and an elevated ACE/ACE2 ratio were observed in exudative effusions. We then differentiated both ACE and ACE2 activities in the exudates according to different diseases, including tuberculosis, pneumonia, and adenocarcinoma. The ACE activity in the tuberculous pleural effusions was significantly higher than in pneumonia and adenocarcinoma effusions, by 2.89 (p < 0.001) and 2.62 (p < 0.001) fold, respectively ( Figure 4A ). In contrast, ACE2 activity in the tuberculous effusions was significantly lower than in pneumonia and adenocarcinoma effusions, by 0.68 (p < 0.05) and 0.58 (p < 0.05) fold, respectively ( Figure 4B ). According to the changes we detected in ACE and ACE2, a significantly higher difference in the ACE/ACE2 ratio in tuberculous effusions (1.72 (1.09-2.52)) compared with ratios in pneumonia (0.32 (0.20-0.50)) and adenocarcinoma (0.43 (0.26-0.67)) effusions was also observed (p < 0.001) ( Figure 4C ).

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