Author: Morokutti-Kurz, Martina; Graf, Christine; Prieschl-Grassauer, Eva
Title: Amylmetacresol/2,4-dichlorobenzyl alcohol, hexylresorcinol, or carrageenan lozenges as active treatments for sore throat Document date: 2017_2_28
ID: q5j3vcfm_45
Snippet: From all AMC/DCBA/HR containing lozenges tested against hCoV OC43 the following were chosen to be further evaluated in various replication inhibition assays due to the following considerations: lozenges #3 and #5 both contain AMC/ DCBA as active ingredients at a similar pH, namely 2.2 and 2.3. Nonetheless, only lozenge #5 was active against hCoV OC43, wherefore it was included into the HRV and Coxsackievirus A10 experiments. To exclude the possib.....
Document: From all AMC/DCBA/HR containing lozenges tested against hCoV OC43 the following were chosen to be further evaluated in various replication inhibition assays due to the following considerations: lozenges #3 and #5 both contain AMC/ DCBA as active ingredients at a similar pH, namely 2.2 and 2.3. Nonetheless, only lozenge #5 was active against hCoV OC43, wherefore it was included into the HRV and Coxsackievirus A10 experiments. To exclude the possibility that a potential antiviral activity is rather a result of the low pH than of the active ingredients, lozenge #4, with the same active agents but a pH of 5.8, was included into the test series. Lozenge #2, with a pH of 5 was tested as it is the only lozenge that contains HR.
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