Author: Morokutti-Kurz, Martina; Graf, Christine; Prieschl-Grassauer, Eva
Title: Amylmetacresol/2,4-dichlorobenzyl alcohol, hexylresorcinol, or carrageenan lozenges as active treatments for sore throat Document date: 2017_2_28
ID: q5j3vcfm_58
Snippet: Taken together, the antiviral effect of the AMC/DCBA and HR containing lozenges varies widely, depending on the specific formulation of the lozenges and the the virus which causes the sore throat. This questions their suitability to be used as causative therapy in a clinical setting, where the disease causing virus mostly remains unknown. In contrast, carrageenan containing lozenges were highly active against all viruses tested, with a minimum su.....
Document: Taken together, the antiviral effect of the AMC/DCBA and HR containing lozenges varies widely, depending on the specific formulation of the lozenges and the the virus which causes the sore throat. This questions their suitability to be used as causative therapy in a clinical setting, where the disease causing virus mostly remains unknown. In contrast, carrageenan containing lozenges were highly active against all viruses tested, with a minimum superiority toward all other lozenges of 2-to 1368-fold for HRV1a and CoV OC43, respectively. Therefore, iota-carrageenan containing lozenges are an appropriate measure to effectively reduce the number of viral particles in the mouth. They can be used as a causative therapy against viral infections of the throat.
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