Author: Parker, Michael T.
Title: An Ecological Framework of the Human Virome Provides Classification of Current Knowledge and Identifies Areas of Forthcoming Discovery Document date: 2016_9_30
ID: t30dg6oj_43
Snippet: Whether humans can harness the beneficial properties of EREs is of much scientific import. For years it has been debated whether gene therapy using retroviral vectors for insertion of genes into an individual would be of more help than harm. Overall the utility of such methods have been tempered by the observed oncogenic potential of such therapies [134] . Recently, studies with retroviral-modified Chimeric Antigen Receptor T-cells (CAR Tcells) h.....
Document: Whether humans can harness the beneficial properties of EREs is of much scientific import. For years it has been debated whether gene therapy using retroviral vectors for insertion of genes into an individual would be of more help than harm. Overall the utility of such methods have been tempered by the observed oncogenic potential of such therapies [134] . Recently, studies with retroviral-modified Chimeric Antigen Receptor T-cells (CAR Tcells) have shown impressive application for the activation of adaptive immunity against cancers, though there have also been morbid failures in this field [135] . The application of retroviral-modified CAR T-cells could presumably be expanded to infectious disease as well. These progressive areas of medical science will continue to be explored and debated well into the future, and better understanding the relationship of EREs with their human hosts will be indispensable for these studies.
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