Selected article for: "airway infection and immune response"
Author: Bourne, Simon; Cohet, Catherine; Kim, Viktoriya; Barton, Anna; Tuck, Andy; Aris, Emmanuel; Mesia-Vela, Sonia; Devaster, Jeanne-Marie; Ballou, W Ripley; Clarke, Stuart; Wilkinson, Tom
Title: Acute Exacerbation and Respiratory InfectionS in COPD (AERIS): protocol for a prospective, observational cohort study
  • Document date: 2014_3_7
    • ID: rbjvc2a6_36
    Snippet: The AERIS study has been initiated to assess the role of infectious pathogens in AECOPD in a well-characterised cohort of patients. The study aims at exploring the dynamics of airway infection and its possible contribution to AECOPD, as well as the potential role of chronic colonization in stable disease. The overall objective of the study will aim at refining the case definition of AECOPD to reflect the possible microbiological aetiology of exac.....
    Document: The AERIS study has been initiated to assess the role of infectious pathogens in AECOPD in a well-characterised cohort of patients. The study aims at exploring the dynamics of airway infection and its possible contribution to AECOPD, as well as the potential role of chronic colonization in stable disease. The overall objective of the study will aim at refining the case definition of AECOPD to reflect the possible microbiological aetiology of exacerbations. This is of note, since there is currently no commonly agreed definition of AECOPD and no current case definition includes a microbiological endpoint. The impact of AECOPD on health-related quality-of-life and healthcare use will be assessed in order to provide a complete picture of disease burden. The interaction between airway infection and systemic manifestations of COPD and nutritional status will also be assessed. Biological specimens collected during the study may also be used for further disease-related testing, including COPD, to explore cell-mediated immune response to specific bacterial antigens, and to develop non-invasive bacterial diagnostic methods.

    Search related documents:
    Co phrase search for related documents
    • nutritional status copd and possible contribution: 1, 2
    • nutritional status copd and potential role: 1, 2
    • nutritional status copd and stable disease: 1, 2
    • nutritional status copd and stable disease chronic colonization potential role: 1, 2
    • overall objective and possible contribution: 1, 2
    • overall objective and potential role: 1, 2, 3
    • overall objective and stable disease: 1, 2, 3, 4, 5
    • overall objective and stable disease chronic colonization potential role: 1, 2
    • overall objective and study overall objective: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37
    • possible contribution and potential role: 1, 2, 3
    • possible contribution and stable disease: 1, 2
    • possible contribution and stable disease chronic colonization potential role: 1, 2
    • possible contribution and study overall objective: 1, 2
    • potential role and stable disease: 1, 2, 3, 4
    • potential role and stable disease chronic colonization potential role: 1, 2
    • potential role and study collect: 1
    • potential role and study overall objective: 1, 2
    • stable disease and study overall objective: 1, 2
    • stable disease chronic colonization potential role and study overall objective: 1, 2