Author: Chen, Hsing I
Title: Acute lung injury and acute respiratory distress syndrome: experimental and clinical investigations Document date: 2011_3_23
ID: xenq90xj_20
Snippet: Our laboratory has reported experimental studies on the effectiveness of several regimen for ALI/ARDS. In conscious rats, regular exercise training alleviates the endotoxin-Journal of Geriatric Cardiology | [email protected]; http://www.jgc301.com induced ALI. Propofol and N-acetylcysteine exert protective effect on the ALI causes by endotoxin, oleic acid and phorbol myristate acetate. We have also provided evidence that insulin possesses ant.....
Document: Our laboratory has reported experimental studies on the effectiveness of several regimen for ALI/ARDS. In conscious rats, regular exercise training alleviates the endotoxin-Journal of Geriatric Cardiology | [email protected]; http://www.jgc301.com induced ALI. Propofol and N-acetylcysteine exert protective effect on the ALI causes by endotoxin, oleic acid and phorbol myristate acetate. We have also provided evidence that insulin possesses anti-inflammatory effect. Pentobarbital is capable of reducing the endotoxin-induced ALI and associated changes. In addition, nicotinamide or niacinamide (soluble B complex) abrogates the ALI caused by ischemia/ reperfusion or endotoxemia. These nonpharmacological and pharmacological therapeutic strategies require further investigations for clinical application.
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