Amylmetacresol/2,4-dichlorobenzyl alcohol, hexylresorcinol, or carrageenan lozenges as active treatments for sore throat

Morokutti-Kurz, Martina; Graf, Christine; Prieschl-Grassauer, Eva

Next, we determined the average lozenge dissolution time under real conditions. Four independent test subjects dissolved a lozenge in their mouth. The timespan needed for complete dissolution was measured, and the medium time calculated from these results (13.34±2.34 minutes; data not shown). In another experiment, we found that the amount of carrageenan liberated from the lozenge is sufficient to guarantee antiviral activity throughout the entire dissolution process (873-62.1 µg/mL carrageenan, from the beginning of dissolution until the end, where almost no lozenge is left). The International Journal of General Medicine is an international, peer-reviewed open-access journal that focuses on general and internal medicine, pathogenesis, epidemiology, diagnosis, monitoring and treatment protocols. The journal is characterized by the rapid reporting of reviews, original research and clinical studies across all disease areas. The manuscript management system is completely online and includes a very quick and fair peer-review system, which is all easy to use. Visit http://www.dovepress.com/testimonials.php to read real quotes from published authors.