Author: Powers, Chelsea N.; Setzer, William N.
Title: An In-Silico Investigation of Phytochemicals as Antiviral Agents Against Dengue Fever Document date: 2016_8_23
ID: q7thhtg3_6
Snippet: DENV NS3 helicase is an essential enzyme for viral replication and has been identified as a potential drug target. The enzyme shows both ATP-hydrolysis activity as well as RNA duplex unwinding activity. These two enzymatic activities are likely coupled with ATPase activity providing the chemical energy for RNA unwinding. Thus, there are two potential targets for DENV NS3 helicase, the RNA binding site [18] and the ATP binding site [12] ......
Document: DENV NS3 helicase is an essential enzyme for viral replication and has been identified as a potential drug target. The enzyme shows both ATP-hydrolysis activity as well as RNA duplex unwinding activity. These two enzymatic activities are likely coupled with ATPase activity providing the chemical energy for RNA unwinding. Thus, there are two potential targets for DENV NS3 helicase, the RNA binding site [18] and the ATP binding site [12] .
Search related documents:
Co phrase search for related documents- ATP hydrolysis activity and RNA duplex: 1
- ATP hydrolysis activity and unwinding activity: 1
- ATP hydrolysis and ATPase activity: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- ATP hydrolysis and chemical energy: 1, 2
- ATP hydrolysis and drug target: 1, 2
- ATP hydrolysis and enzymatic activity: 1
- ATP hydrolysis and essential enzyme: 1
- ATP hydrolysis and RNA duplex: 1, 2, 3
- ATP hydrolysis and unwinding activity: 1, 2, 3, 4
- ATP hydrolysis and viral replication: 1, 2
- ATPase activity and drug target: 1, 2, 3, 4
- ATPase activity and enzymatic activity: 1, 2, 3, 4
- ATPase activity and essential enzyme: 1
- ATPase activity and potential drug target: 1
- ATPase activity and potential drug target identify: 1
- ATPase activity and potential target: 1, 2, 3
- ATPase activity and RNA duplex: 1, 2, 3, 4, 5, 6
- ATPase activity and unwinding activity: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
- ATPase activity and viral replication: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
Co phrase search for related documents, hyperlinks ordered by date