Selected article for: "CAVV divergence prevalence and divergence prevalence"

Author: Zirkel, Florian; Kurth, Andreas; Quan, Phenix-Lan; Briese, Thomas; Ellerbrok, Heinz; Pauli, Georg; Leendertz, Fabian H.; Lipkin, W. Ian; Ziebuhr, John; Drosten, Christian; Junglen, Sandra
Title: An Insect Nidovirus Emerging from a Primary Tropical Rainforest
  • Document date: 2011_6_14
  • ID: ulwo6i38_21
    Snippet: Our data on CAVV prevalence and divergence demonstrate how a virus may evolve through emergence from a pristine rainforest habitat into surrounding areas of less host biodiversity due to anthropogenic modification. Critically, while extending out of the primary forest habitat, the virus seemed to narrow its genetic diversity while increasing in prevalence (reverse dilution effect [13, 60, 61] ). Further investigations are needed to untangle if th.....
    Document: Our data on CAVV prevalence and divergence demonstrate how a virus may evolve through emergence from a pristine rainforest habitat into surrounding areas of less host biodiversity due to anthropogenic modification. Critically, while extending out of the primary forest habitat, the virus seemed to narrow its genetic diversity while increasing in prevalence (reverse dilution effect [13, 60, 61] ). Further investigations are needed to untangle if the higher prevalence of CAVV in human settlements relates to a higher density of hosts (insects or vertebrates) or virus adaption. This principal understanding is necessary to develop experimental ecology models of virus-vector dynamics. This study underlines the importance of linking ecosystem biology and virus ecology to unravel the role of ecosystem modifications in the emergence of novel pathogens.

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