Author: Kang, Soo Jung; Kim, Nam Su
Title: Association of Toll-like receptor 2-positive monocytes with coronary artery lesions and treatment nonresponse in Kawasaki disease Document date: 2017_7_31
ID: tk1bxztw_43
Snippet: This study showed that FTLR2% before the initial treatment of patients with KD was significantly high in the CAL (+) group than that in the CAL () group, and this was a more sensitive, predictive parameter for CALs than sIL10. Furthermore, FTLR2% tended to be higher in IVIG nonresponders compared to that in the IVIG res ponders, and this frequency could predict IVIG resistance with a sensitivity comparable to that of sIL10. To the best of our kno.....
Document: This study showed that FTLR2% before the initial treatment of patients with KD was significantly high in the CAL (+) group than that in the CAL () group, and this was a more sensitive, predictive parameter for CALs than sIL10. Furthermore, FTLR2% tended to be higher in IVIG nonresponders compared to that in the IVIG res ponders, and this frequency could predict IVIG resistance with a sensitivity comparable to that of sIL10. To the best of our knowle dge, our study is the first clinical study to utilize FTLR2% to predict CAL development and IVIG resistance in patients with KD and to compare its feasibility with that of sIL10.
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